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Ty (a 50 year old male patient) suffering from pneumonia was given 1000mg IV bolus dose of the antibiotic Z.

Ty (a 50 year old male patient) suffering from pneumonia was given 1000mg IV bolus dose of the antibiotic Z. The following table contains hisTY (a 50-year-old male patient) suffering from pneumonia was given 1000 mg IV bolus dose of the antibiotic Z. The following table contains his plasma concentrations: Time (min) Concentration (mg/L) 5min 7.8mg/L 30min 5.7mg/L 60min 3.9mg/L 100min 2.4mg/L 200min 0.7mg/L 1) Plot the data. (5 marks) 2) Calculate the pharmacokinetic parameters for antibiotic Z in this patient. (5 marks) 3) What can you derive about antibiotic Z from the calculated pharmacokinetic parameters? (5 marks)

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