Question: Complement plays key roles in the elimination of bacteria. Bacteria must develop strategies to overcome these activities in order to survive.
A. Identify three major roles of complement.
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1.) opsonization and phagocytosis
2.)cell lysis
3.) chemotaxis
B. For EACH of the three roles, identify ONE complement element which is responsible for that role and explain how that complement element is formed.
C. Propose a bacterial evasion strategy (known or potential) that might realistically be employed to divert or prevent the formation of EACH of these three elements.
D. Choose ONE of these evasive maneuvers and suggest a possible counter-strategy the immune system might employ to overcome it.
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